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What causes rheumatoid arthritis?

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  Rheumatoid arthritis (RA) is an autoimmune disorder, which means that the immune system mistakenly attacks the body's own tissues, primarily affecting the joints. While the exact cause of RA is not fully understood, several factors are believed to contribute to its development: Genetic Factors: Certain genetic markers are associated with an increased risk of developing rheumatoid arthritis. Individuals with a family history of RA might be more susceptible to the condition. Autoimmune Response: In individuals with a genetic predisposition, environmental triggers like infections or other factors might cause the immune system to malfunction. Instead of protecting the body, the immune system attacks the synovium, the lining of the membranes that surround the joints. Inflammation: The immune system's attack on the synovium leads to chronic inflammation. This inflammation can cause joint damage, pain, swelling, and stiffness. Synovial Changes: Inflammation in the synovium can lead ...